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James Varani Selected Research

MDI 301

8/2015MDI 301 suppresses myeloid leukemia cell growth in vitro and in vivo without the toxicity associated with all-trans retinoic acid therapy.
10/2009The Göttingen minipig for assessment of retinoid efficacy in the skin: comparison of results from topically treated animals with results from organ-cultured skin.
11/2004Activity of MDI-301, a novel synthetic retinoid, in xenografts.
11/2003Separation of retinoid-induced epidermal and dermal thickening from skin irritation.

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James Varani Research Topics

Disease

14Neoplasms (Cancer)
01/2022 - 01/2002
10Inflammation (Inflammations)
01/2022 - 06/2004
9Hyperplasia
11/2010 - 12/2004
8Carcinoma (Carcinomatosis)
07/2015 - 01/2003
7Colonic Neoplasms (Colon Cancer)
10/2015 - 01/2003
7Wounds and Injuries (Trauma)
11/2010 - 12/2002
6Polyps
01/2020 - 03/2010
6Psoriasis (Pustulosis Palmaris et Plantaris)
10/2010 - 08/2004
5Nephrogenic Fibrosing Dermopathy
06/2012 - 02/2009
3Fibrosis (Cirrhosis)
01/2016 - 06/2012
3Renal Insufficiency (Renal Failure)
02/2012 - 02/2009
3Basal Cell Carcinoma (Rodent Ulcer)
10/2005 - 06/2003
2Body Weight (Weight, Body)
01/2022 - 01/2016
2Adenoma (Adenomas)
01/2018 - 01/2018
2Carcinogenesis
01/2016 - 06/2013
2Leukemia
08/2015 - 01/2015
2Erythema
08/2015 - 11/2003
2Skin Diseases (Skin Disease)
11/2006 - 08/2004
2Acute Lung Injury
04/2006 - 06/2004
2Skin Ulcer
08/2005 - 03/2005
1Ulcerative Colitis
01/2020
1Cicatrix (Scar)
02/2017
1Sepsis (Septicemia)
10/2016
1Alcoholic Fatty Liver
01/2016
1Hypoxia (Hypoxemia)
01/2016
1Colorectal Neoplasms (Colorectal Cancer)
01/2016
1End Stage Liver Disease
01/2016
1Non-alcoholic Fatty Liver Disease
01/2016
1Macular Degeneration (Age-Related Maculopathy)
10/2015
1Telangiectasis (Telangiectasia)
08/2015
1Myeloid Leukemia (Leukemia, Myelocytic)
08/2015
1Experimental Melanoma
01/2015
1B-Cell Leukemia (Leukemia, B Cell)
01/2015
1Osteoporosis
12/2013
1Body Remains
06/2012
1Adenomatous Polyps
01/2012
1Pruritus (Itching)
01/2012

Drug/Important Bio-Agent (IBA)

12MineralsIBA
01/2022 - 10/2009
10CalciumIBA
01/2020 - 01/2003
9Matrix Metalloproteinases (MMPs)IBA
08/2015 - 12/2002
9RetinoidsIBA
08/2015 - 11/2003
8Proteins (Proteins, Gene)FDA Link
01/2020 - 04/2006
7Calcium-Sensing ReceptorsIBA
07/2015 - 01/2003
6CollagenIBA
01/2022 - 12/2002
5Biological ProductsIBA
01/2020 - 03/2008
5GadoliniumIBA
12/2012 - 02/2009
4Tretinoin (Retinoic Acid)FDA LinkGeneric
08/2015 - 11/2003
4MDI 301IBA
08/2015 - 11/2003
4Contrast MediaIBA
06/2012 - 02/2009
3EnzymesIBA
01/2022 - 10/2005
3AquaminIBA
01/2020 - 07/2015
3Matrix Metalloproteinase 1 (Interstitial Collagenase)IBA
12/2010 - 07/2005
3LigandsIBA
10/2010 - 12/2005
3ThiazolidinedionesIBA
11/2006 - 08/2004
2MagnesiumIBA
01/2020 - 07/2015
2Trace Elements (Biometals)IBA
01/2020 - 01/2018
2Pharmaceutical PreparationsIBA
10/2015 - 06/2013
2Interleukin-1 (Interleukin 1)IBA
03/2015 - 10/2010
2AntibodiesIBA
01/2015 - 04/2006
2AntigensIBA
01/2015 - 12/2004
2gadodiamide (Omniscan)FDA Link
06/2012 - 11/2010
2Clobetasol (Clobetasol Propionate)FDA LinkGeneric
11/2010 - 05/2009
2Padma 28IBA
11/2010 - 03/2005
2Bz-423IBA
03/2008 - 04/2005
2beta CateninIBA
10/2007 - 01/2003
2Cadherins (E-Cadherin)IBA
10/2007 - 01/2003
22,4-thiazolidinedione (thiazolidinedione)IBA
11/2006 - 12/2005
2AmphiregulinIBA
04/2006 - 04/2005
2GenisteinIBA
04/2006 - 12/2004
2PPAR gammaIBA
12/2005 - 08/2004
2Thioctic Acid (Lipoic Acid)IBA
08/2005 - 08/2004
2Matrix Metalloproteinase 9 (Gelatinase B)IBA
07/2005 - 06/2004
2AlitretinoinFDA Link
11/2004 - 11/2003
1MucinsIBA
01/2020
1Keratin-20 (Cytokeratin 20)IBA
01/2019
1RNA (Ribonucleic Acid)IBA
01/2018
1Histones (Histone)IBA
10/2016
1polycationsIBA
10/2016
1Virulence Factors (Pathogenicity Factors)IBA
10/2016
1Dietary CalciumIBA
01/2016
1IronIBA
01/2016
1Dietary IronIBA
01/2016
1nasIBA
01/2016
1MetalsIBA
01/2016
1Verteporfin (Visudyne)FDA Link
10/2015
1Transcription Factors (Transcription Factor)IBA
10/2015
1STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
10/2015
1Retinoic Acid Receptors (Retinoic Acid Receptor)IBA
08/2015
1Vitamin DFDA LinkGeneric
07/2015
1Erlotinib Hydrochloride (CP 358,774)FDA Link
03/2015
1Monoclonal AntibodiesIBA
01/2015
1Laminin ReceptorsIBA
01/2015
1Lanthanoid Series Elements (Lanthanides)IBA
12/2012
1GD3 ganglioside (GD(3))IBA
02/2012
1SaltsIBA
02/2012

Therapy/Procedure

5Therapeutics
08/2015 - 11/2004
2Chemoprevention
07/2015 - 03/2010
1Diet Therapy (Therapy, Diet)
01/2016
1Phototherapy (Light Therapy)
10/2015
1Fat-Restricted Diet (Diet, Fat Restricted)
06/2012